Chemotherapeutic agents do not act exclusively on tumor cells. The normal structures that renew themselves constantly, as bone marrow, hair and mucosa of the gut are also affected by the action of chemotherapy.

However, because normal cells have an expected recovery time, unlike the anaplastic cells, it is possible that chemotherapy is applied repeatedly, since the observed time interval required for the recovery of bone marrow and the lining of the gut. For this reason, chemotherapy is applied in periodic cycles.
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