Mechanisms of action and classification of anticancer drugs
The agents used in cancer treatment affects both the normal and neoplastic cells, but they cause more damage to malignant cells than to normal tissues due to quantitative differences between the metabolic processes of these two cell populations.
The cytotoxic are not lethal to tumor cells selectively. Differences between the growth of malignant cells and normal cells and small biochemical differences observed between them probably combine to produce their specific effects.